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Case Study

Automating Pathogen Detection to Rapid Commercial Scale

Overview

From Prototype to Production-Ready Platform

A fast-growing food safety technology company sought to transform the way foodborne pathogens are identified in agricultural environments — replacing slow, manual processes with an integrated, automated platform capable of delivering results weeks ahead of conventional methods. Ascential delivered full-scale engineering, design, and manufacturing services to bring this complex system from prototype to commercial readiness.

Faster pathogen detection compared to traditional methods
6–10 Weeks 0
Reduction in time to market, enabling earlier commercial entry and product adoption
0 %
Manufacturing that maintained cell viability and detection accuracy across large sample sizes
Scalable 0

The Challenge

Identifying foodborne pathogens in agricultural environments has long been one of the most critical — and most cumbersome — processes in food safety management. Existing methods were manual, error-prone, and slow. Delays in detection translated directly into delayed intervention, increasing the risk of contamination events with significant public health and operational consequences.

The client recognized an opportunity to fundamentally change this paradigm. Their vision was to build a platform that could combine cell transport technology with molecular techniques to rapidly identify and quantify pathogens in food production settings — detecting them weeks ahead of current practices. But translating that scientific concept into a commercial-scale product required deep engineering expertise, systems integration capability, and proven manufacturing rigor.

Their goals were clear:

Speed

Compress Time-to-Result

Reduce pathogen detection turnaround by weeks compared to conventional methods, enabling faster intervention decisions.

Throughput

Enable High-Volume Sample Processing

Build a system capable of processing large sample sizes at scale without sacrificing cell viability or detection accuracy.

Integration

Unify Complex Technologies in a Single System

Combine cell transport technology with molecular identification techniques in a single, automated platform.

Commercial Readiness

Accelerate Time-to-Market

Partner with a full-service engineering and manufacturing provider to bring the platform to market quickly and at scale.

Ascential's Solution

Ascential engaged as a full development partner, taking ownership of the engineering, design, and manufacturing lifecycle from the outset. Rather than inheriting a partially developed system and working in isolation, our cross-functional team — spanning mechanical, fluidic, optical, software, and systems engineering — worked in parallel across all phases of development to accelerate timelines without compromising quality.

By engaging early and owning the full development lifecycle, Ascential was able to refine the core technologies and integrate them into a unified automated system — one that could be manufactured consistently at scale while maintaining the performance standards the client required.

The platform Ascential engineered and brought to production is the first of its kind to combine cell transport technology with molecular techniques for food production applications. Designed to keep cells viable while rapidly identifying and quantifying pathogens in complex samples, the system delivers results 6–10 weeks ahead of current conventional practices. Key elements of Ascential’s solution included:

  • Technology Refinement: Ascential refined both the cell transport and molecular identification technologies to ensure reliable integration within a single, automated system — addressing the core compatibility and performance challenges that would have prevented scale-up.
  • Automation Architecture: The platform was designed for high-throughput, automated pathogen detection, eliminating the manual, error-prone steps that characterized previous approaches and introducing consistent, reproducible results across large sample volumes.
  • Scalable Contract Manufacturing: Ascential applied its contract manufacturing expertise to ensure the platform could be produced at scale with consistent quality across all units. Supply chain management services were integrated from the start to keep production timelines on track.

Technical Capabilities Delivered

The platform integrates a sophisticated combination of subsystems, all designed, validated, and documented in-house by Ascential’s engineering team:

CapabilityWhat Ascential Built
Cell Transport IntegrationEngineered the cell transport subsystem to maintain cell viability throughout the detection workflow, preserving sample integrity from intake through analysis.
Molecular IdentificationIntegrated molecular techniques for rapid, accurate pathogen identification and quantification within a single automated platform.
Automation & ControlsDesigned high-throughput automated processing with custom control system electronics, integrated sensors, and safety interlocks.
Fluidic HandlingPrecision fluidic systems for accurate reagent and sample dispensing throughout the detection workflow.
Software & FirmwareComplex workflow scheduling, firmware, and user interface software to support seamless, reliable operation.
Scalable ManufacturingContract manufacturing processes established to produce units consistently at scale with validated quality controls.
Supply Chain ManagementEnd-to-end supply chain oversight to ensure production timelines were met and component quality was maintained.

Key Results

From prototype refinement through commercial-scale manufacturing, Ascential served as a full-service technical program management partner. The completed platform exceeded performance targets across every key dimension:

  • 6–10 weeks faster pathogen detection compared to traditional methods, directly improving food safety response times and enabling faster intervention decisions.
  • Scalable manufacturing achieved that maintained cell viability and detection accuracy across large sample sizes, validating the platform’s readiness for broad commercial deployment.
  • 15% reduction in commercialization timeline, allowing the client to enter the market earlier and accelerate product adoption.

Why It Matters

Foodborne illness remains a persistent and costly public health challenge worldwide. The ability to detect pathogens weeks earlier than current practices gives food producers, processors, and regulators a meaningful window to act — reducing contamination risk, protecting consumers, and limiting the operational and reputational consequences of an outbreak.

For the client, this platform represents a commercially ready, scalable product that brings a genuinely differentiated capability to market. For the food industry more broadly, it sets a new standard for what rapid, automated pathogen detection can achieve.

Ascential’s contribution extended well beyond engineering execution. By owning the full development and manufacturing lifecycle — and integrating supply chain management from the outset — we ensured that speed to market and product performance advanced together, rather than in tension.